Intracytoplasmic Sperm Injection (ICSI)

ICSI at Birla Fertility & IVF

ICSI is a form of fertility treatment used in case of male infertility. In this procedure, a single healthy sperm is individually selected from the semen sample with the help of an advanced micromanipulation station and injected into the centre of an egg (cytoplasm). The fertilised egg is then transferred to the female partner’s uterus.


When the male has an infertility factor such as low sperm count, poor sperm morphology and poor sperm motility

When previous attempts of IVF treatment were unsuccessful or had unexpectantly low fertilisation rates (none or few eggs were fertilised)

When sperm was obtained surgically through TESA or PESA

When sperm quality on the day of egg collection was not suitable for IVF due to natural variations in semen

When frozen sperm is used, from men with a history of vasectomy, chemotherapy or radiotherapy

The ICSI Process

Before you begin your IVF-ICSI cycle, you and your partner will undergo an individual assessment to identify the most suitable fertility treatment. An IVF-ICSI cycle involves the following procedures/steps:

Step 1 – Ovarian stimulation

Step 2 – Egg Retrieval

Step 3 – Fertilisation

Step 4 – Embryo Transfer

Step 1 – Ovarian stimulation

Similar to a conventional IVF cycle, you will need to undergo hormone therapy to stimulate the ovaries to produce more eggs than usual. During this phase, you will be closely monitored with routine ultrasound scans and blood tests to check how the follicles (fluid filled sacs in which eggs develop) are growing.

Step 2 – Egg Retrieval

Step 3 – Fertilisation

Step 4 – Embryo Transfer

Experts Speak

A brief about ICSI

Dr. Meeta Sharma

Fertility Specialist

Frequently Asked Questions

What is the full form of ICSI?

ICSI is the acronym for intracytoplasmic sperm injection. It is an advanced IVF treatment that involves injecting a single sperm directly into the egg using a fine glass needle.

When should I consider ICSI?

ICSI is recommended for couples with male infertility such as low count and poor-quality sperm or if the sperm was surgically retrieved. It is also recommended when conventional IVF therapy is ineffective or when genetic tests (PGS/PGD) are required.

What are the risks of ICSI?

Apart from the risks that come with conventional IVF treatment, there is a risk that the eggs may be damaged when they are cleaned or injected with sperm during an ICSI-IVF cycle.

What is the success rate of ICSI the first time?

ICSI is very successful in helping sperm fertilise the egg. However, like IVF several factors affect the success rate such as maternal age and cause of infertility.

Patient Testimonials

The Birla Fertility team is very helpful with every step of the IVF treatment. After discussing and a few check-ups, the doctor suggested an intracytoplasmic sperm injection procedure. The whole process was so smooth. Thank you for all your support!

Ratan and Rahul

All the staff members of the Birla Fertility & IVF are genuinely good and honest. Everyone in the hospital is very caring. Their friendliness and helpful nature are very much appreciated! Thank you, Birla Fertility.

Payal and Sunil

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