Intracytoplasmic Sperm Injection (ICSI)
Intracytoplasmic sperm injection (ICSI) is a specialised form of in vitro fertilisation (IVF) primarily used to treat severe male factor infertility. The procedure involves injecting a single sperm directly into a mature egg to promote fertilisation.

What is ICSI?

ICSI is a form of IVF commonly used when male infertility is the cause of not conceiving. It involves injecting sperm directly into a mature egg to promote fertilisation. ICSI is recommended for couples with male factor infertility, such as low sperm count or poor sperm motility. It helps to overcome these issues and achieve fertilisation. ICSI can also be used in cases of previous failed fertilisations with IVF or unexplained infertility cases.
Birla Fertility & IVF is a leading fertility clinic in India that offers comprehensive ICSI services as part of its IVF treatments. They have experienced embryologists who perform the ICSI procedure using advanced equipment and techniques. They also provide individualised treatment plans and support patients throughout the ICSI process.
When is ICSI Recommended?
ICSI is primarily recommended in the following cases:
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Male Factor Infertility: ICSI is often used to treat severe male infertility issues such as low sperm count or poor sperm motility.
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Previous Failed Fertilisation with IVF: If a couple has experienced poor or no fertilisation rates using standard IVF in the past, ICSI may be recommended.
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Need for Surgical Sperm Retrieval: ICSI enables the use of sperm retrieved surgically from the testicles or epididymis.
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Use of Frozen or Thawed Sperm: Frozen sperm from men with a history of vasectomy, chemotherapy, or radiotherapy may have reduced fertilising capacity. ICSI may be recommended to such men to maximise the chances of fertilisation.
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Advanced Maternal Age: ICSI may be suggested to older women to increase fertilisation rates as egg quality declines with increasing age.

How is ICSI Done?

The key steps involved in the ICSI procedure are as follows:
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Initial Phase: The female partner undergoes fertility testing, including an examination of the uterus and fallopian tubes, as well as hormonal assessment.
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Ovarian Stimulation: The female partner is given hormonal medications. This stimulates the ovaries to produce mature eggs. Once the eggs are ready, a trigger shot is given to allow the eggs to be released from the follicles.
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Egg Retrieval and Sperm Collection: The eggs are surgically retrieved using a minor procedure. The male partner provides a sperm sample, either through ejaculation or surgical extraction, if needed.
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ICSI Fertilisation: A single sperm is selected and injected directly into the mature egg using a tiny needle under a microscope.
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Embryo Development: The fertilised eggs (embryos) are cultured for 3-5 days, allowing them to develop to the blastocyst stage before embryo transfer.
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Embryo Transfer: One or more embryos are selected for transfer based on their quality and development. Using an ultrasound-guided catheter, the selected embryo(s) are placed into the woman’s uterus. This allows the embryo(s) to implant and continue developing.
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Pregnancy Test: Approximately 2 weeks after the embryo transfer, a pregnancy test is conducted to confirm the success of the treatment.
Why Choose Us
Choosing the right fertility clinic is crucial for starting your family. At Birla Fertility & IVF, we offer personalised care with expert specialists guiding you every step of the way. Our advanced labs and outstanding success rates have helped over 2,30,000 patients achieve their dream of parenthood.
Things to Remember for ICSI
Before the Treatment
- Initial Consultation: Meet with a fertility specialist to discuss your infertility issues.
- Lifestyle Changes: Maintain a healthy diet and exercise regularly to optimise fertility. Engage in regular, moderate exercise to stay physically fit.
- Medications and Ovarian Stimulation: The female partner will need to take fertility medications to stimulate her ovaries. This ensures the eggs are at the optimal stage of maturity for the ICSI procedure.
- Egg Retrieval and Sperm Collection: The female partner will receive a trigger shot to allow the eggs to mature fully before retrieval. The male partner should provide a semen sample on the day of egg retrieval.
During the Treatment
- First, the woman undergoes ovarian stimulation with fertility medications to produce multiple eggs.
- A single healthy sperm is selected and injected directly into each mature egg using a hollow glass needle under high magnification. This process is repeated for each egg.
After the Treatment
- The injected eggs are placed in an incubator to allow for fertilisation and embryo development over the next 3–5 days.
- The healthiest embryo(s) are then selected and transferred back into the woman's uterus.
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ICSI Cost in Different Cities
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ICSI Treatment in Different Cities
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ICSI Doctors in Different Cities
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