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Diminished Ovarian Reserve (DOR) Treatment in India

Diminished ovarian reserve (DOR) means that the number of eggs remaining in the ovaries is lower than expected for a woman’s age. It can make conception more challenging, particularly as age also affects egg quality. However, having diminished ovarian reserve does not mean that pregnancy is impossible. The right diminished ovarian reserve treatment depends on factors such as age, ovarian reserve, ovulation, fallopian tube health, sperm quality and previous fertility history. Depending on these findings, a fertility specialist may recommend trying naturally, medicines, IUI, IVF or other fertility options.

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Causes of Diminished Ovarian Reserve

There are several possible causes of diminished ovarian reserve, although in some women no specific cause can be identified.

Natural Ageing

Age is one of the main factors associated with declining ovarian reserve. Women are born with a finite number of eggs and both egg number and quality generally decline with age.

Genetic Factors

Certain genetic conditions and chromosomal changes can affect ovarian function and may lead to reduced ovarian reserve at a younger age. A family history of early menopause may also be relevant.

Endometriosis

Endometriosis can affect the ovaries and may be associated with reduced ovarian reserve. Endometriomas and their treatment can sometimes affect ovarian tissue.

Ovarian Surgery

Surgery for ovarian cysts, endometriomas or other ovarian conditions can sometimes reduce the amount of functioning ovarian tissue. The impact depends on the type and extent of surgery.

Chemotherapy and Radiation Therapy

Some cancer treatments can damage ovarian follicles and affect ovarian function. Women who may undergo such treatment can discuss fertility preservation before starting therapy.

Autoimmune Disorders

Certain autoimmune conditions may be associated with impaired ovarian function. If suspected, the doctor may recommend further evaluation along with routine fertility testing.

Smoking and Lifestyle Factors

Smoking is associated with faster reproductive ageing and can negatively affect fertility. Healthy lifestyle habits cannot restore lost ovarian reserve, but avoiding smoking, maintaining a healthy weight, eating a balanced diet and exercising regularly can support overall health.

Diagnosis of Diminished Ovarian Reserve

No single test can provide a complete picture of ovarian reserve. Doctors generally combine medical history, hormone tests and ultrasound findings.

Medical History and Fertility Assessment

The doctor may review menstrual cycles, age, previous pregnancies or fertility treatments, ovarian surgery, endometriosis, family history and previous cancer treatment. A semen analysis may also be advised because male fertility factors can affect the overall treatment plan.

Anti-Müllerian Hormone (AMH) Test

AMH is produced by developing ovarian follicles. An AMH blood test helps estimate ovarian reserve and may provide an indication of how the ovaries could respond to stimulation. AMH does not measure egg quality and cannot independently predict natural pregnancy.

Follicle-Stimulating Hormone (FSH) Test

FSH plays a role in follicular development. It may be measured during the early part of the menstrual cycle as part of an ovarian reserve assessment. FSH is interpreted along with age, AMH, AFC and other clinical findings.

Antral Follicle Count (AFC) Ultrasound

AFC is measured through a transvaginal ultrasound. The doctor counts the small antral follicles visible in the ovaries, which provides an estimate of the available follicle pool. AFC can also help the fertility specialist plan ovarian stimulation for treatments such as IVF.

Treatment Options for Diminished Ovarian Reserve

There is currently no treatment that can restore the number of eggs in the ovaries. Treatment instead focuses on making the best use of the eggs available and choosing an approach suited to the woman's fertility goals.

Individualised Fertility Planning

Treatment begins with understanding the woman's overall fertility picture. The specialist may review age, menstrual history, AMH, FSH, antral follicle count (AFC), ovulation, fallopian tube health and the partner's semen analysis.

Based on these findings, the doctor can discuss whether trying naturally, using medicines or considering assisted reproductive treatment would be appropriate.

Controlled Ovarian Stimulation

Controlled ovarian stimulation uses fertility medicines to encourage the ovaries to develop multiple follicles. It may be used as part of IUI or IVF treatment.

With diminished ovarian reserve, the response to stimulation may be lower because fewer follicles are available. The stimulation protocol and medicines are therefore selected according to the woman's ovarian reserve and expected response.

Intrauterine Insemination (IUI)

IUI is a relatively simple fertility treatment. Around the time of ovulation, prepared sperm is placed directly into the uterus to give the sperm a better chance of reaching the egg.

IUI may be considered when the fallopian tubes are open and there are no major fertility concerns that call for IVF. Your age, ovarian reserve and your partner’s sperm health will also be considered before choosing IUI.

In Vitro Fertilisation (IVF)

IVF involves the use of fertility medicines for the development of the follicles in the ovaries. The egg is retrieved and fertilised with sperm in the laboratory, where an embryo is produced and transferred into the uterus.

In the case of diminished ovarian reserve, fewer eggs may be retrieved during the course of the IVF process. However, despite this, IVF can still be an effective choice for you. The doctor evaluates your age, diagnosis and prior treatments and makes the decision for the IVF cycle.

Donor Egg IVF (When Recommended)

In certain instances, using your own eggs may not be the right choice. In situations like diminished ovarian reserve or when previous IVF cycles have produced no suitable embryos, donor egg IVF can bring some hope. In donor egg IVF, a screened donor's egg is fertilised with sperm and the resulting embryo is transferred to the uterus. Your fertility specialist will explain when this option may be worth considering and what the treatment involves.

Fertility Preservation

Fertility preservation through egg freezing is becoming a popular option among women who are not yet ready to conceive but want to consider it in the future.

Egg freezing involves ovarian stimulation, egg retrieval and freezing of mature eggs for potential future use. With diminished ovarian reserve, fewer eggs may be retrieved, so age and ovarian reserve are important considerations when discussing this option.

Cost of Diminished Ovarian Reserve Treatment in India

Treatment for diminished ovarian reserve in India may differ in price according to different considerations such as the suggested treatment, medications, tests as well as the fertility centre. The final cost can be affected by additional lab tests, embryo freezing or cryopreservation and other examinations that need to be performed prior to or during the cycle.

Below is an estimation:

Treatment

Approximate Cost in India

Fertility assessment

₹2,000 – ₹10,000

Ovulation induction

₹5,000 – ₹15,000 per cycle

IUI

₹10,000 – ₹25,000 per cycle

IVF

₹1,00,000 – ₹2,50,000 per cycle

Donor Egg IVF

₹2,00,000 – ₹4,00,000 or more

Egg freezing

₹1,00,000 – ₹2,50,000 per cycle

It is advisable to ask the fertility centre for a detailed cost estimate and understand which services are included before starting treatment.

Why Choose Birla Fertility & IVF for Diminished Ovarian Reserve Treatment in India?

People trust Birla Fertility & IVF for diminished ovarian reserve treatment for the following reasons: 

  • Experienced fertility specialists: Consult with fertility experts who assess ovarian reserve along with other factors affecting fertility, thus providing a comprehensive treatment approach. 
  • Detailed fertility evaluation: A detailed assessment may be suggested, including tests like AMH, FSH, AFC ultrasound, along with examination of tubal health. Semen analysis for male partner can be advised for a complete analysis.
  • Multiple treatment options: At Birla Fertility & IVF, individuals get access to all key fertility treatments including ovulation induction, IUI, IVF, donor egg IVF and fertility preservation.
  • Advanced embryology laboratories: IVF treatment is supported by dedicated embryology laboratories and internationally accepted laboratory protocols.
  • Personalised treatment planning: Treatment plans are based on age, ovarian reserve, fertility history and individual treatment response.
  • Transparent treatment discussions: Doctors explain available options, the treatment process and expected considerations before you proceed.
  • Multiple centres across India: Birla Fertility & IVF has more than 50 fertility centres across India, making expert fertility care more accessible.

Step-by-Step Diminished Ovarian Reserve (DOR) Treatment Process

Consultation
Ovarian Reserve Testing
Fertility Evaluation
Choosing the Right Treatment
Monitoring and Review

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