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Preimplantation Genetic Diagnosis

Birla Fertility & IVF offers comprehensive PGD (Preimplantation Genetic Diagnosis) services to detect and prevent the transmission of specific genetic conditions to offspring. This treatment, also known as preimplantation genetic testing for monogenic/single-gene diseases (PGT-M), ensures healthier outcomes for future generations.

Egg Freezing

What is Preimplantation Genetic Diagnosis?

Preimplantation Genetic Diagnosis (PGD) is a technique used to detect genetic abnormalities in embryos created through in vitro fertilisation (IVF). This is done by removing a few cells from the embryo and analysing them for chromosomal abnormalities.

PGD is done to:

  1. Detect Genetic Abnormalities: PGD helps identify genetic abnormalities such as Down syndrome, Turner syndrome, and other chromosomal disorders.

  2. Improved IVF Success Rates: PGD enhances IVF success rates by selecting embryos with the correct number of chromosomes.

  3. Reduce the Risk of Miscarriage: PGD reduces miscarriage risk by selecting embryos with a lower likelihood of chromosomal abnormalities.

  4. Enhance Family Planning: PGD aids couples in family planning by selecting embryos with the desired genetic characteristics.

Why Consider Preimplantation Genetic Diagnosis?

The reasons why preimplantation genetic diagnosis (PGD) is recommended are as follows:

  1. Family History: For couples with a family history of genetic conditions or chromosomal issues.

  2. Genetic Conditions: For those carrying genetic conditions like Thalassemia, Cystic Fibrosis, or inheritable cancers.

  3. Recurrent Miscarriages: For couples with a history of recurrent miscarriages caused by genetic conditions.

  4. Reduce Genetic Risk: PGD allows the selection of genetically healthy embryos, reducing the risk of passing on genetic disorders.

  5. Enhance IVF Success: By identifying and transferring only chromosomally normal embryos, PGD can improve IVF success rates.

  6. Avoid Difficult Decisions: PGD offers an alternative to invasive prenatal testing.

How Is Preimplantation Genetic Diagnosis Performed?

Here is a concise overview of how preimplantation genetic diagnosis (PGD) is performed:

  1. IVF Cycle: The process begins with an IVF cycle, where eggs are retrieved and fertilised with sperm to create embryos.

  2. Embryo Development: The embryos are cultured and allowed to develop to the blastocyst stage for 5 or 6 days after fertilisation.

  3. Embryo Biopsy: A small number of cells are removed from each embryo, usually from the trophectoderm layer, which will form the placenta. This can be done on day 3 (cleavage stage) or day 5/6 (blastocyst stage).

  4. Genetic Testing: The biopsied cells are sent to a genetic testing lab to analyse specific genetic disorders or chromosomal abnormalities. Techniques such as PCR, FISH, CGH, or next-generation sequencing are used for this purpose.

  5. Embryo Freezing: After the biopsy, the embryos are frozen using vitrification. This helps to preserve them until the genetic test results are available.

  6. Results: The genetic testing results are typically available within 1-2 weeks after the biopsy. If the embryos are deemed suitable, they are thawed and transferred to the uterus.

  7. Embryo Transfer: One or more genetically normal embryos are selected for transfer to the uterus. This selection is based on the PGD results and the embryo’s developmental potential.

Why Choose Us

Choosing the right fertility clinic is crucial for starting your family. At Birla Fertility & IVF, we offer personalised care with expert specialists guiding you every step of the way. Our advanced labs and outstanding success rates have helped over 2,30,000 patients achieve their dream of parenthood.

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Best-in-class
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With a team of 120 fertility experts, state-of-the-art embryology labs, and world-class technology, we achieve outstanding pregnancy rates

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95% Patient
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We offer personalized treatment plans and comprehensive fertility services, ensuring exceptional fertility care under one roof.

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100% Transparent &
Affordable Pricing

We are committed to making world-class fertility treatments affordable and accessible. We offer fixed price all-inclusive packages and 0% EMI options with no hidden charges.

Our Doctors

Dr. Muskaan Chhabra

Lajpat Nagar, Delhi

Dr. Muskaan Chhabra

MBBS, MS (Obstetrics & Gynaecology), ACLC (USA)

14+
Years of experience: 
  2000+
  Number of cycles: 
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Dr. Swati Mishra

Kolkata, West Bengal

Dr. Swati Mishra

MBBS, MS (Obstetrics & Gynaecology)

15+
Years of experience: 
  4000+
  Number of cycles: 
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Dr. Prachi Benara

Gurgaon – Sector 14, Haryana

Dr. Prachi Benara

MBBS (Gold Medalist), MS (OBG), DNB (OBG), PG Diploma in Reproductive and Sexual health

16+
Years of experience: 
  7000+
  Number of cycles: 
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Frequently Asked Questions

Preimplantation genetic diagnosis can detect the risk of approximately 600 genetic diseases including thalassaemia, sickle cell disease, cystic fibrosis, certain inherited cancers, Huntingdon’s disease, muscular dystrophies, and fragile-X. These tests have to be designed specially for each couple.
Gender determination is illegal in India and not done with PGD.
There is no evidence that suggests babies born after PGD are at the risk of having congenital problems or developmental issues.
PGD involves collecting cells from the embryo. This can damage or destroy the embryo. However, advances in the field of assisted reproductive technology and embryology have significantly improved survival rates for embryos through PGD. In rare cases, PGD may be unsuccessful in detecting the issue or give incorrect results.

Patient Testimonials

Recommended IVF by other clinics conceived naturally at Birla Fertility & IVF

We came in for a fallopian tube test, expecting to be recommended IVF. However, our doctor at Birla Fertility & IVF suggested a minor treatment and provided exceptional support and guidance. Thanks to this thoughtful approach, we conceived naturally. We are deeply grateful to the team at Birla Fertility & IVF for their care. With the right support, you’ll be well taken care of. Trust the process and go with the flow!

Jasleen & Jaswinder

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Doctor’s expertise turned our parenthood dream into reality

Our doctor at Birla Fertility & IVF made all the difference in our journey. From addressing all our queries to prescribing only what was needed, the support and comfort we received were invaluable. We are grateful to the entire team at Birla Fertility & IVF

Sakshi & Inderjeet

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Success after multiple IVF failures

After multiple failures at other clinics our family doctor recommended us to visit Birla Fertility & IVF. We received exceptional care and support from the entire team of doctors and nurses who were there to support us every step of our journey. Thanks for making our dream come true!

Simran & Arun Dubey

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