The main diagnostic method for teratozoospermia is semen analysis. In this test, a semen sample is tested in a laboratory to evaluate several characteristics of the semen. A typical semen analysis can assess:

• Sperm Concentration: The number of sperm present in a sample. It helps assess whether sperm count falls within the expected range or not.
• Motility: How well the sperm moves.This helps determine whether sperm can move effectively towards the egg or not.
• Morphology: The size, shape, and structure of individual sperm cells. The abnormal shape of the sperm can affect their ability to fertilise an egg.
• Sperm Volume: The amount of semen produced. It helps assess whether the volume of ejaculate falls within the expected range or not.
• Other Parameters: Varies depending on laboratory and clinical situation. These parameters can include pH, vitality, and other indicators of semen quality.

To test for sperm teratozoospermia, a sample is prepared in a laboratory and the sperm are examined under a microscope. Sperm are evaluated according to accepted morphological criteria and the percentage meeting specific criteria for normal morphology is recorded.