
Live Birth After Recurrent Implantation Failure and Chronic Endometritis
After 13 years of primary infertility, multiple IUI attempts and three unsuccessful IVF cycles, this couple came to Birla Fertility & IVF, Gorakhpur, after repeatedly receiving negative pregnancy results.
Case Snapshot
Journey Timeline

1. Multiple Failed Treatments

2. Uterine Evaluation

3. Polyp & Endometritis Treatment

4. Personalised Embryo Transfer

5. Healthy Live Birth
The Barriers They Faced
Recurrent Implantation Failure
Despite several fertility treatments, including IVF with both own and donor gametes, pregnancy had not been achieved.
Endometrial Polyp
An endometrial polyp was identified on ultrasound and removed hysteroscopically before embryo transfer.
Chronic Endometritis
Persistent inflammation of the endometrium was subsequently confirmed and treated before proceeding with transfer.
Long Treatment History
The couple had already experienced repeated treatment failure over many years, making careful reassessment especially important.
Doctor's Quote

“The key was to tailor every aspect of care to this patient's unique needs, balancing safety, comfort, and clinical effectiveness.”— Dr. Akriti Gupta
The Treatment Plan that made the Difference

Hysteroscopy and Polypectomy
The uterine cavity was evaluated hysteroscopically and the endometrial polyp was removed before embryo transfer.

Treatment of Chronic Endometritis
The identified endometrial inflammation was managed before proceeding to the transfer stage.

Donor-Oocyte IVF and Blastocyst Culture
A donor-oocyte IVF cycle using the husband's sperm was planned, with embryos cultured to the blastocyst stage.

Embryo Assessment
PGT-A was used to provide additional information about embryo chromosome status in this selected case.

Individualised Transfer Planning
ERA findings were considered while planning transfer timing, with PRP also used as part of the personalised endometrial preparation strategy.

The Outcome
The treatment resulted in a positive pregnancy test, a confirmed clinical pregnancy and ultimately the delivery of a healthy 2.2 kg baby girl.

The Outcome
A Story of Healing Before Hope
After years of unsuccessful treatment, evaluation of the uterine environment identified factors that needed to be addressed before another embryo transfer. By treating the endometrial polyp and chronic endometritis and then individualising embryo and transfer planning, the team approached the case as a combination of interconnected factors rather than another routine IVF cycle.
