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Cerebral Palsy with Epilepsy: Successful Live Birth Through Personalised IVF

Fertility Files – Real Cases of Infertility Challenges

When Safety Came First: A Carefully Planned Journey to Motherhood

Cerebral palsy. Epilepsy. Long-term medication. For her, the journey to motherhood wasn’t just about fertility it was about safety, stability, and navigating multiple medical complexities together. Natural conception wasn’t possible. And every step forward had to be carefully planned, balancing her neurological condition with the goal of a healthy pregnancy. But with the right care, even complex challenges don’t have to close the door to parenthood.

- Birla Fertility & IVF, Thrissur (Dr. Venugopal)
Dr. Venugopal

Case Snapshot

Patient AgeFemale: 27 years
ChallengesCerebral palsy (spastic diplegia), epilepsy on long-term medication, mental health condition, high-risk pregnancy considerations
TreatmentIVF with ICSI, controlled ovarian stimulation, single embryo transfer, multidisciplinary care approach
OutcomeSuccessful pregnancy and birth of a healthy baby girl
Timeline~8–10 months

Journey Timeline

Complex Challenges

1. Complex Challenges

Personalised Plans

2. Personalised Plans

Safe Retireval & Transfer

3. Safe Retireval & Transfer

Guided Transfer

4. Guided Transfer

Successful Pregnancy

5. Successful Pregnancy

The Barriers They Faced

Neurological Condition

Cerebral palsy affecting mobility and overall treatment adaptability.

Epilepsy & Medication Use

Potential impact on fertility, egg quality, and pregnancy safety.

Mental Health Considerations

Required ongoing emotional and psychological support.

Pregnancy Risk Management

Need to minimise complications during gestation.

Treatment Sensitivity

Every step required careful monitoring and individualisation.

Doctor's Quote

Doctor
“The key was to tailor every aspect of care to this patient's unique needs, balancing safety, comfort, and clinical effectiveness.”
Dr. Venugopal

The Treatment Plan that made the Difference

Controlled Ovarian Stimulation (Antagonist Protocol)

Designed to optimize egg retrieval while maintaining patient comfort and safety.

Ovum Pick-Up Outcome

15 oocytes retrieved → 10 mature (MII) ICSI performed → 8 successfully fertilised

Embryo Development

Day 5: 1 blastocyst cryopreserved Day 6: 1 additional blastocyst cryopreserved

Single Embryo Transfer Strategy

A frozen embryo transfer (FET) was performed with a single Day 5 blastocyst, carefully chosen to minimise risks associated with multiple pregnancy.

A Story of Safe, Thoughtful Parenthood

This case highlights that fertility care is not one-size-fits-all especially in medically complex situations. With the right approach: – Neurological conditions can be safely managed alongside fertility treatment – Risks can be minimised through single embryo transfer – Pregnancy can be achieved without compromising maternal health At Birla Fertility & IVF, a multidisciplinary, patient-first approach helped transform a high-risk case into a safe and successful outcome. Because sometimes, success isn’t just about achieving pregnancy it’s about doing it in the safest way possible, for both mother and child.
Outcome Background

The Outcome

β-hCG confirmed a positive pregnancy.

She carried the pregnancy successfully and delivered a healthy baby girl. Both mother and baby are stable and doing well.

Every journey is unique. With science and empathy, parenthood is possible.