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Azoospermia, Tubal Factor Infertility, and Haemorrhagic Cyst Leading to an Ongoing Twin Pregnancy

Azoospermia, Tubal Factor Infertility, and Haemorrhagic Cyst Leading to an Ongoing Twin Pregnancy

After three years of primary infertility, this couple came to Birla Fertility & IVF after discovering that both partners were facing fertility challenges. The female partner had a blocked fallopian tube and a haemorrhagic ovarian cyst, while the male partner was diagnosed with azoospermia, requiring surgical sperm retrieval. The couple strongly wished to conceive using the husband's own sperm, making treatment planning especially important. With advanced surgical sperm retrieval, personalised IVF treatment, and expert embryology support, they achieved a successful twin pregnancy.

- Birla Fertility & IVF, Indore (Dr. Payal Jaiswal)
Dr. Payal Jaiswal

Case Snapshot

Patient AgeFemale: 27 years | Male: Not specified
ChallengesPrimary infertility for 3 years, tubal blockage, haemorrhagic ovarian cyst, azoospermia requiring TESA, uncertainty regarding sperm retrieval, preference to use self-sperm
TreatmentPersonalised ovarian stimulation, Testicular Sperm Aspiration (TESA), ICSI, blastocyst culture, frozen embryo transfer (FET)
OutcomeSuccessful implantation, ongoing twin pregnancy, expected due date in October 2026
TimelineThree years of infertility followed by a personalised IVF cycle with surgical sperm retrieval and frozen embryo transfer.

Journey Timeline

Complex Challenges

1. Complex Challenges

Personalised Plans

2. Personalised Plans

Safe Retireval & Transfer

3. Safe Retireval & Transfer

Guided Transfer

4. Guided Transfer

Successful Pregnancy

5. Successful Pregnancy

The Barriers They Faced

Tubal Factor Infertility

A blocked fallopian tube prevented natural fertilisation, making assisted reproduction necessary.

Haemorrhagic Ovarian Cyst

The presence of an ovarian cyst required careful monitoring during ovarian stimulation and treatment planning.

Azoospermia

The male partner had no sperm present in the ejaculate and required Testicular Sperm Aspiration (TESA) for sperm retrieval.

Uncertainty Around Sperm Retrieval

As a diagnostic TESA had not been performed previously, there was uncertainty about whether viable sperm would be available on the day of egg retrieval.

Desire to Use Self-Sperm

The couple expressed a strong preference to achieve pregnancy using the husband's own sperm rather than donor sperm.

Need to Maximise Embryo Development

Given the potential limitations in sperm quality, every opportunity to achieve healthy embryo development had to be optimised.

Doctor's Quote

Doctor
“The key was to tailor every aspect of care to this patient's unique needs, balancing safety, comfort, and clinical effectiveness.”
— Dr. Payal Jaiswal

The Treatment Plan that made the Difference

Personalised Ovarian Stimulation

The patient responded well to ovarian stimulation, resulting in the retrieval of 25 oocytes, including 19 mature (MII) oocytes suitable for fertilisation.

Surgical Sperm Retrieval with TESA

On the day of treatment, Testicular Sperm Aspiration (TESA) was successfully performed, and viable sperm were retrieved despite abnormal sperm characteristics.

ICSI and Blastocyst Culture

The retrieved sperm were used for ICSI, allowing successful fertilisation. The embryos showed excellent developmental potential, progressing from Grade A compacting morulae to the blastocyst stage.

Selection of High-Quality Embryos

A total of 15 blastocysts were successfully developed, with eight high-quality blastocysts cryopreserved on Day 5 for future use.

Personalised Frozen Embryo Transfer

Two Grade 5AA blastocysts were transferred during a carefully planned frozen embryo transfer (FET) cycle after optimising the uterine environment for implantation.

A Story of Teamwork in Managing Combined Infertility

This case highlights how azoospermia, tubal factor infertility, and an ovarian cyst can be successfully overcome through coordinated, personalised fertility care. By combining TESA, ICSI, advanced blastocyst culture, and carefully planned frozen embryo transfer, the clinical team helped the couple achieve pregnancy using the husband's own sperm despite significant uncertainty at the start of treatment. It demonstrates the value of multidisciplinary expertise, advanced embryology, and individualised treatment planning in helping couples with complex infertility achieve successful pregnancy outcomes.
Outcome Background

The Outcome

The personalised treatment approach resulted in:

Positive β-hCG confirming successful implantation Ongoing twin pregnancy Healthy progression of pregnancy Expected due date in October 2026

Every journey is unique. With science and empathy, parenthood is possible.