Fertility Files – Real Cases of Infertility Challenges

At 43, Choosing to Try with Their Own Embryo

43 years old. Low ovarian reserve. High genetic risk. Most would say the odds are stacked against you. At this stage, it’s not just about getting pregnant, it’s about whether eggs are viable, whether embryos will form, and whether they will be chromosomally normal. But for this couple, one decision mattered deeply: They wanted to try with their own gametes.

- Birla Fertility & IVF, Jaipur, (Dr. Priyanka Yadav)

Case Snapshot

Patient AgeFemale: 43 years | Male: 50 years

ChallengesAdvanced maternal age, poor ovarian reserve, high risk of chromosomal abnormalities

TreatmentIVF with advanced embryology, blastocyst culture, PGT-A, single embryo transfer

OutcomeSuccessful pregnancy (ongoing)

Timeline~6–9 months

Journey Timeline

1. Complex Challenges

2. Personalised Plans

3. Safe Retireval & Transfer

4. Guided Transfer

5. Successful Pregnancy

The Barriers They Faced

Advanced Maternal Age (43)

Reduced egg quality and higher aneuploidy risk.

Poor Ovarian Reserve

Limited number of eggs available.

Embryo Viability Concerns

Not all embryos would be genetically normal.

Need for Self Gametes

Required optimising outcomes without donor support.

Precision-Driven Success

Each step had to be carefully planned and executed.

Doctor's Quote

“The key was to tailor every aspect of care to this patient's unique needs, balancing safety, comfort, and clinical effectiveness.”

— Dr. Priyanka Yadav

The Treatment Plan that made the Difference

Controlled Ovarian Stimulation

Designed to retrieve the best possible number of viable oocytes.

IVF with Advanced Embryology Support

Fertilisation followed by extended blastocyst culture to assess embryo potential.

Embryo Development

5 blastocysts formed – 3 good-quality – 2 average-quality

PGT-A (Genetic Testing)

Performed on the 3 best embryos → 1 euploid (chromosomally normal) embryo identified

Single Embryo Transfer

The euploid embryo was transferred under optimised clinical conditions to maximise implantation success.

A Story of Choosing Possibility

This case is a powerful reminder that age and low ovarian reserve do not automatically close the door to parenthood. Even when: – Egg numbers are low – Genetic risks are high – The margin for error is small Success is still possible, with the right combination of advanced embryology, genetic screening (PGT-A), and personalised care. At Birla Fertility & IVF, this approach helped turn a high-risk case into a hopeful journey, proving that sometimes, all it takes is one healthy embryo to change everything.

The Outcome

β-hCG confirmed a positive pregnancy.

The pregnancy is progressing well, currently in the 4th month.