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HIV, Endometriosis, and Low Ovarian Reserve Didn’t Stand in Their Way

Case Study: Real Cases of Infertility Challenges

Against Every Medical Odd: HIV, Endometriosis, and Low Ovarian Reserve Didn’t Stand in Their Way

HIV. Endometriosis. Low ovarian reserve. Each diagnosis felt like another door closing. He was HIV positive. She had Grade 4 endometriosis and a diminished ovarian reserve. For years, they lived with the fear of passing something on to each other or to their future child. <br> On paper, parenthood seemed impossible. But science has a way of rewriting stories when paired with care that truly listens. Today, they are holding a healthy, HIV negative baby girl, living proof that parenthood is not defined by a diagnosis

- Birla Fertility & IVF, Gurgaon (Dr. Prachi Benara & Dr. Rashmika Nanda)
Dr. Muskaan Chhabra

Case Snapshot

Patient AgeFemale: Early 30s | Male: Mid 30s
Key ChallengesMale partner HIV-positive (on stable HAART, undetectable viral load), Grade 4 Endometriosis, Low Ovarian Reserve, Suppressed Menstrual Cycle
OutcomeHealthy, full-term pregnancy and delivery of an HIV-negative baby girl
HistoryProlonged infertility, medical complexities, and emotional fatigue
Treatment IVF with specialised ART protocols and infectious disease–safe semen processing
TimelineApproximately 6–8 months

Journey Timeline

Complex Challenges

1. Complex Challenges

Personalised Plans

2. Personalised Plans

Safe Retireval & Transfer

3. Safe Retireval & Transfer

Guided Transfer

4. Guided Transfer

Successful Pregnancy

5. Successful Pregnancy

The Barriers They Faced

Risk of HIV Transmission

Natural conception was unsafe, requiring stringent ART protocols.

Semen Processing

Samples had to be processed under strict infectious disease protocols in a specialised lab.

Grade 4 Endometriosis

Reduced fertility potential and created uterine challenges.

Suppressed Menstrual Cycle

Years of therapy had disrupted her natural cycle.

Low Ovarian Reserve:

Limited egg supply meant stimulation had to be timed and planned precisely.

Emotional Exhaustion

The couple needed both psychological support and medical precision.

Doctor's Quote

Doctor
“The key was to tailor every aspect of care to this patient's unique needs, balancing safety, comfort, and clinical effectiveness.”
Dr. Muskaan Chhabra

The Treatment Plan that made the Difference

Restoring Menstrual Cycle

Medications were prescribed to re-establish her natural cycle before IVF.

Safe Semen Preparation

The husband’s HAART continued, and semen was processed to remove viral particles.

Controlled Ovarian Stimulation

Tailored protocols retrieved quality eggs without overburdening her body.

Embryo Creation & Preservation

10 oocytes retrieved → 5 viable embryos developed and frozen.

Endometriosis Suppression & Uterine Readiness

The uterus was optimised for safe implantation.

Embryo Transfer

A single embryo transfer was performed with precision to ensure safety.

Case Summary: Their Journey to Parenthood

The couple had been married for 5 years. The husband was HIV-positive but on stable HAART (Highly Active Antiretroviral Therapy), with viral load suppressed to undetectable levels.
The wife had Grade 4 endometriosis, suppressed menstrual cycles due to prolonged hormonal therapy, and low ovarian reserve. After years of waiting, failed attempts, and emotional fatigue, they turned to Birla Fertility & IVF, determined to make their dream of parenthood a reality.
This case is proof that HIV does not mean the end of parenthood dreams. With modern ART, interdisciplinary care, and tailored protocols, science and compassion can help achieve parenthood.
At Birla Fertility & IVF, we believe that no challenge is too great when approached with precision medicine and empathetic care. For this couple, what once seemed impossible became their most beautiful reality, holding their healthy baby in their arms.
Outcome Background

The Outcome

IVF was successful. The couple conceived on the first embryo transfer.

After a full-term pregnancy, they welcomed a healthy baby girl weighing 3 kgs, HIV-negative and thriving.

Every journey is unique. With science and empathy, parenthood is possible.